Kidney disease, also known as chronic kidney disease, is a life-long condition in which the kidney gradually loses function. About 26 million American adults have chronic kidney disease, according to the National Kidney Foundation. Millions of others are at an increased risk for developing the disease and are not aware of it. With the progression of kidney disease, wastes build up in your blood. As a result, complications can occur such as high blood pressure, high potassium levels which can impair heart health, central nerve damage, anemia, poor nutritional health, weak bones, and a decreased immune response.