Feel-Good Exercise Hormone Irisin Is Real
/Scientists in the US have found that a feel-good exercise hormone called irisin DOES exist. Previously thought to be a myth but new research team from Dana-Farber Cancer Institute used mass spectrometry to look for irisin in blood samples of individuals after exercise. The form of mass spectrometry used in the new study was far more accurate and reliable in measuring irisin. Found that these people had released the exercise hormone from their body, which activates fat cells to increase energy turn over
Research published in the journal Cell Metabolism and found that concentrations are present in sedentary individuals.
It significantly increased in individuals undergoing aerobic interval training
- Irisin is in fact being regulated by endurance exercise in humans
- The discovery of Irisin’s discovery in 2012 was exciting because it points to a reason why exercise keeps us healthy
In mice:
- When irisin levels were increased, blood and metabolism improved
- Results from human studies are still mixed as to what kinds of exercise raise irisin
- Data suggests that high-intensity training regiments are particularly effective
- state-of-the-art technology, the researchers have proven beyond doubt that irisin is real.
- Previous studies using commercially available kits called “ELISA” kits detected the presence of irisin, by recognizing an antigen, in samples, which could produce inconsistent results with irisin
- Confirming the existence of irisin is a step towards potentially developing therapeutics that could benefit individuals with metabolic disease and obesity
- Drugs could target the pathways that are activated by irisin
- These would mimic the effects of exercise
· Further studies are necessary to fully understand how the hormone works in humans
· Study shows that irisin circulates in humans and it increases after exercise
· Now need to explore biological function of irisin in humans