Prostate gland enlargement, otherwise known as benign prostatic hyperplasia, BPH, or benign prostatic hypertrophy, is a condition that most often affects older men. As men get older, the prostate gland naturally becomes enlarged. This can put pressure on the bladder and urethra, causing problems with urination. Over 50 percent of men in their 60s and up to 90 percent of men in their 70s and 80s have some symptoms of an enlarged prostate.