For the first time since the 1980’s, the Food and Drug Administration has approved an over-the-counter (OTC) retinoid medication for acne.  Differin Gel 0.1% (adapalene) has been used to treat acne since 1996 but in a stronger form.  Now the gel, at a lower concentration, will be available to consumers as a safe and effective option for treating acne.

Anyone who has ever suffered from acne knows how this common skin condition can lead to poor self-esteem, anxiety, and depression affecting a person’s quality of life.  

Acne is a skin condition involving the oil glands at the base of hair follicles.  It typically begins during puberty when the sebaceous (oil) glands are activated by the male hormones produced by the adrenal glands of both males and females.

Mild cases of acne usually run its course without leaving scarring but some people endure more severe acne marring the face, neck, back, chest and/or shoulders with permanent scarring and disfigurement.  

Differin gel 0.1% is a retinoid medication containing vitamin A-like chemicals helping to reduce acne outbreaks by preventing dead skin cells from clogging pores.  The stronger form of differin gel (0.3% strength) is still available but only as a prescription through a doctor.  This milder form now available to the public without a prescription can help people who are not able to see a dermatologist.

There have been several studies evaluating this new OTC acne medication showing good results for improving acne leading to better compliance and satisfaction by the user.

Like with most acne medications, users are advised to stay out of the sun avoiding sunburn and are reminded that skin irritation can occur during the first few weeks of use.  It is advised to always use a sunscreen each day when using differin gel 0.1%.

Women who planning to become pregnant, are pregnant or breastfeeding should inquire with their doctor on the safety of using differin gel 0.1%.  At this time there have been no studies conducted using this medication on pregnant women so the safety of use is unknown.  However birth defects have occurred in babies from women who were pregnant using retinoid drugs for acne.